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The domestic automated laboratory assembly line enters the academic field of vision


Abstract: With the continuous advancement of detection and analysis technology, laboratory and clinical detection instruments have gradually expanded from semi-automatic analysis in the past to fully automatic analysis instruments.The working mode has also developed from the automatic work of a single instrument in the past to the full laboratory automation (TLA) of the existing assembly line, or full process automation.And this new concept and technology will also revolutionize the hospital inspection management model.

Automated testing laboratory products began to enter China around 2009. The market demand has not yet been fully released, but it has initially shown huge market potential.With the advancement of hierarchical medical care, the demand for blood laboratories has gradually shifted from large tertiary hospitals to primary hospitals. The increase in the sample size of some secondary and above hospitals has made the demand for blood laboratories in secondary hospitals also great. .On the other hand, the domestic blood pipeline market is completely monopolized by foreign companies, and the security of national health data, which is more valuable than economic benefits, cannot be guaranteed at all.What is gratifying is that the equipment R&D and production capabilities led by Chinese companies in this field are constantly increasing.If the research and development of laboratory automation equipment led by the Chinese can be realized, digital management can be used to build norms, safety, lean, and efficiency, and at the same time provide management predictions and suggestions for the statistics and analysis of gene banks, regional high incidence, epidemics, and infectious diseases. ; Save medical resources and rationally allocate medical resources for the age of aging; establish reasonable medical insurance coverage and the insurance tendency of the insurance industry, so as to help China's health management industry enter the era of scientific management and rational decision-making more quickly.This study takes the functional design of a domestic automated laboratory assembly line as an example to describe the development status of domestic automated laboratory assembly line products and prospects for future development trends.


TOP 1

The market trend of the use of automated laboratory assembly line products

The assembly line is a part of laboratory automation. The Chinese people's understanding of the laboratory only stays at the level of measurement automation. It is designed to save labor, for consistency, and to improve the convenience of using a single brand. They are all closed systems. The brand (manufacturer) perspective is not a design concept from the perspective of a hospital.

At present, the assembly lines sold in the Chinese market are dominated by system integrators, and the automation systems are all OEM. The design concept is to improve the use and convenience of users (hospitals).A key problem in the entire equipment system is that the non-modular combined instruments or instruments connected by different manufacturers are mainly completed in the form of robots.The assembly and maintenance of the machine lack a unified technical standard. The parts and structure of the machine are completely different according to the design of each manufacturer. This has caused the problem of easy purchase and difficult repair of laboratory assembly line products.

At present, hundreds of hospitals have established clinical laboratory automation systems around the world, mainly in the United States, Japan, Australia, etc., and there are not many users of the entire laboratory automation system.In China, a few hospitals have introduced the B-fronted laboratory automation system, but most of them purchase several smaller subsystems in the entire automation system, such as simple blood cell analysis plus push and staining subsystems, and biochemicals. Pretreatment of the system, as well as the pretreatment of the biochemical and immune subsystems, etc., to establish a "semi-automatic" laboratory.Such a laboratory has the advantages of saving working hours, low comprehensive cost and high cost performance. It is the current basic hospital laboratory plan.


TOP 2

The design concept of the new laboratory automation assembly line in the future

In the future new laboratory automation assembly line system, there is a single-machine modular design, and each module as a basic unit can be independent of the model.They can also be combined or added at will, bringing convenience and flexibility to the inspection work.However, for the products of other manufacturers that have not been uniformly designed, there are many problems such as inconsistent production technology, mismatched connection components, and software redesign.The ideal solution is to support the integration of multiple systems such as the sample pre-classification system to form a large system, and then combine the common standards in the existing market to construct a fully automated equipment system.The laboratory simplifies and optimizes the work process through the automation system, shortens the TAT (laboratory time), standardizes the inspection process, saves human resources and improves laboratory biosafety.However, the introduction and construction of the assembly line is a comprehensive system engineering.In order to achieve efficient operation, optimize and improve the process according to the specific conditions of hospital laboratory personnel, specimens, instruments, information and logistics.

TOP 3

The future development trend of new laboratory automation assembly line technology

The full laboratory automation system is a multi-professional, multi-technical and complex dense pole system engineering. The complex technical system requires a balanced, reliable and stable integrated technology, which is different from a stand-alone product, with bright spots and outstanding advantages. , Complicated automation and intelligent systems are similar to aerospace systems and high-speed rail systems. The emphasis is on scientific balance, mature technology, and stability. This is why there are very few companies that can produce such system products.There needs to be a promising and passionate technical concept, and a team system and incentive system that attract multi-disciplinary professional and technical personnel and work together for a long time.When a system is complex to a certain level, it does not need bright spots or advantages. What is needed is an all-round monopoly advantage in this segmented field.Compared with the traditional laboratory automation assembly line equipment, the new laboratory automation assembly line has made major breakthroughs in several aspects such as equipment technology, supply service mode, and market positioning.

With the advent of the 5G era, a test of the Internet of Things is gradually taking shape.With the application of cloud technology, a laboratory IoT system is being realized.An invisible competition is rapidly accelerating among the developed countries. This is also the point of control and the next core competition point for countries to seize.A gold mine of inspection data gradually appeared in front of users.The data economy has officially become a part of economic life.The new laboratory automation pipeline adopts database technology, logic and mathematics technology of time sequence and beat, and edge computing technology of measurement process.Combine sample testing, scheduling, transportation, result review, judgment, equipment operating status, reagent status, quality control, calibration status, data analysis, and some artificial intelligence technologies.In the operation of the laboratory, a complex intelligent machine network is formed to realize complex management and control without human intervention.


TOP 4

Thoughts on the Production and Supply Process of New Type Laboratory Automatic Assembly Line Equipment in the Future

When applying the assembly line, the laboratory must also consider how to meet the specification requirements in a good way to ensure the quality of the test.Another issue that attracts attention in pipeline applications is how to quickly and effectively start emergency plans when the pipeline is down due to hardware or software.We borrowed UMS's offline emergency response method and backed up the offline interface program.When the assembly line system fails, as long as the testing instrument can operate normally, we can quickly switch to the "offline" mode for stand-alone operation to ensure the smooth progress of daily work.




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